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1

Diaries for Intensive Care Unit Survivors (DISCUSS): Perspectives of patients and family members regarding psychological support

Aitken, Leanne M., Rattray, Janice, Kenardy, Justin, Hull, Alastair M., Ullman, Amanda, Le Brocque, Robyne, Mitchell, Marion, Davis, Chelsea, Macfarlane, Bonnie

Journal:

Australian Critical Care

Year:

2016

Language:

english

File:

PDF, 135 KB

english, 2016

2

Patient-derived explants (PDEs) as a powerful preclinical platform for anti-cancer drug and biomarker discovery

Powley, Ian R., Patel, Meeta, Miles, Gareth, Pringle, Howard, Howells, Lynne, Thomas, Anne, Kettleborough, Catherine, Bryans, Justin, Hammonds, Tim, MacFarlane, Marion, Pritchard, Catrin

Journal:

British Journal of Cancer

Year:

2020

Language:

english

File:

PDF, 2.03 MB

english, 2020

3

Increased hepatotoxicity of tumor necrosis factor–related apoptosis-inducing ligand in diseased human liver

Xandra Volkmann, Ute Fischer, Matthias J. Bahr, Michael Ott, Frank Lehner, Marion MacFarlane, Gerald M. Cohen, Michael P. Manns, Klaus Schulze-Osthoff, Heike Bantel

Journal:

Year:

2007

Language:

english

File:

PDF, 921 KB

english, 2007

4

Dose-dependent induction or depression of cysteine conjugate β-lyase in rat kidney by N-acetyl-S-(1,2,3,4,4-pentachloro-1,3-butadienyl)-L-cysteine

Marion Macfarlane, Miles Schofield, Nicola Parker, Lilian Roelandt, Morell David, Edward A. Lock, Laurie J. King, Peter S. Goldfard, Gordon G. Gibson

Journal:

Year:

1993

Language:

english

File:

PDF, 1.42 MB

english, 1993

5

Caspase-3 expression is reduced, in the absence of cleavage, in terminally differentiated normal oral epithelium but is increased in oral squamous cell carcinomas and correlates with tumour stage

Angela Hague, John W Eveson, Marion MacFarlane, Suzanne Huntley, Nari Janghra, Selvam Thavaraj

Journal:

The Journal of Pathology

Year:

2004

Language:

english

File:

PDF, 412 KB

english, 2004

6

Receptor-selective TRAIL Mutants Target Lymphoid Tumor cells for Apoptosis via TRAIL-R1: Implications for Therapy

Marion MacFarlane, Susan L. Kohlhaas, Michael J. Sutcliffe, Martin J.S. Dyer, Gerald M. Cohen

Journal:

Year:

2008

Language:

english

File:

PDF, 80 KB

english, 2008

7

TRAIL signals to apoptosis in chronic lymphocytic leukaemia cells primarily through TRAIL-R1 whereas cross-linked agonistic TRAIL-R2 antibodies facilitate signalling via TRAIL-R2

Alessandro Natoni, Marion MacFarlane, Satoshi Inoue, Renata Walewska, Aneela Majid, Deborah Knee, David R. Stover, Martin J. S. Dyer, Gerald M. Cohen

Journal:

British Journal of Haematology

Year:

2007

Language:

english

File:

PDF, 399 KB

english, 2007

8

The adenomatous polyposis coli protein and retinoblastoma protein are cleaved early in apoptosis and are potential substrates for caspases

Browne, Sara J, MacFarlane, Marion, Cohen, Gerald M, Paraskeva, Christos

Journal:

Cell Death & Differentiation

Year:

1998

Language:

english

File:

PDF, 282 KB

english, 1998

9

Apoptosis and disease: a life or death decision

MacFarlane, Marion, Williams, Ann C.

Journal:

Year:

2004

Language:

english

File:

PDF, 535 KB

english, 2004

10

Initiation of Apaf-1 translation by internal ribosome entry

Coldwell, Mark J, Mitchell, Sally A, Stoneley, Mark, MacFarlane, Marion, Willis, Anne E

Journal:

Year:

2000

Language:

english

File:

PDF, 309 KB

english, 2000

11

Mechanisms of resistance to TRAIL-induced apoptosis in primary B cell chronic lymphocytic leukaemia

MacFarlane, Marion, Harper, Nicholas, Snowden, Roger T, Dyer, Martin J S, Barnett, Georgina A, Pringle, J Howard, Cohen, Gerald M

Journal:

Year:

2002

Language:

english

File:

PDF, 250 KB

english, 2002

12

Cysteine conjugate β-lyase of rat kidney cytosol: Characterization, immunocytochemical localization, and correlation with hexachlorobutadiene nephrotoxicity

Marion MacFarlane, John R. Foster, G.Gordon Gibson, Laurence J. King, Edward A. Lock

Journal:

Toxicology and Applied Pharmacology

Year:

1989

Language:

english

File:

PDF, 11.56 MB

english, 1989

13

Assessing the cytotoxic profile of novel endoperoxide derivatives

James W. Firman, Marion MacFarlane, B. Kevin Park, Amy E. Mercer

Journal:

Year:

2011

Language:

english

File:

PDF, 65 KB

english, 2011

14

Doxorubicin synergises with a TRAIL-R1-specific ligand to selectively target TRAIL-resistant breast tumour cells for apoptosis

Shambhavi Naik, Davina Twiddy, Roshna Mistry, Jennifer M. Edwards, Gerald M. Cohen, Rosemary A. Walker, Marion MacFarlane

Journal:

Year:

2011

Language:

english

File:

PDF, 109 KB

english, 2011

15

Disassembly of the JIP1/JNK molecular scaffold by caspase-3-mediated cleavage of JIP1 during apoptosis

Mahesh Vaishnav, Marion MacFarlane, Martin Dickens

Journal:

Experimental Cell Research

Year:

2011

Language:

english

File:

PDF, 1.06 MB

english, 2011

16

The ‘complexities’ of life and death: Death receptor signalling platforms

Laura S. Dickens, Ian R. Powley, Michelle A. Hughes, Marion MacFarlane

Journal:

Experimental Cell Research

Year:

2012

Language:

english

File:

PDF, 893 KB

english, 2012

17

Promoter-specific or all wRAPped up in the genome?

Marion MacFarlane

Journal:

Trends in Genetics

Year:

2001

Language:

english

File:

PDF, 43 KB

english, 2001

18

SMAC agonists blaze the TRAIL to tumor cells

Marion MacFarlane

Journal:

Trends in Cell Biology

Year:

2002

Language:

english

File:

PDF, 15 KB

english, 2002

19

Protein Complexes Activate Distinct Caspase Cascades in Death Receptor and Stress-Induced Apoptosis

Shawn B. Bratton, Marion MacFarlane, Kelvin Cain, Gerald M. Cohen

Journal:

Experimental Cell Research

Year:

2000

Language:

english

File:

PDF, 289 KB

english, 2000

20

Reconstitution of the Death-Inducing Signaling Complex Reveals a Substrate Switch that Determines CD95-Mediated Death or Survival

Michelle A. Hughes, Nicholas Harper, Michael Butterworth, Kelvin Cain, Gerald M. Cohen, Marion MacFarlane

Journal:

Year:

2009

Language:

english

File:

PDF, 1.91 MB

english, 2009

21

The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs

Tencho Tenev, Katiuscia Bianchi, Maurice Darding, Meike Broemer, Claudia Langlais, Fredrik Wallberg, Anna Zachariou, Juanita Lopez, Marion MacFarlane, Kelvin Cain, Pascal Meier

Journal:

Year:

2011

Language:

english

File:

PDF, 41 KB

english, 2011

22

cIAPs Block Ripoptosome Formation, a RIP1/Caspase-8 Containing Intracellular Cell Death Complex Differentially Regulated by cFLIP Isoforms

Maria Feoktistova, Peter Geserick, Beate Kellert, Diana Panayotova Dimitrova, Claudia Langlais, Mike Hupe, Kelvin Cain, Marion MacFarlane, Georg Häcker, Martin Leverkus

Journal:

Year:

2011

Language:

english

File:

PDF, 2.20 MB

english, 2011

23

The Ripoptosome, a Signaling Platform that Assembles in Response to Genotoxic Stress and Loss of IAPs

Tencho Tenev, Katiuscia Bianchi, Maurice Darding, Meike Broemer, Claudia Langlais, Fredrik Wallberg, Anna Zachariou, Juanita Lopez, Marion MacFarlane, Kelvin Cain, Pascal Meier

Journal:

Year:

2011

Language:

english

File:

PDF, 1.83 MB

english, 2011

24

A Death Effector Domain Chain DISC Model Reveals a Crucial Role for Caspase-8 Chain Assembly in Mediating Apoptotic Cell Death

Laura S. Dickens, Robert S. Boyd, Rebekah Jukes-Jones, Michelle A. Hughes, Gemma L. Robinson, Louise Fairall, John W.R. Schwabe, Kelvin Cain, Marion MacFarlane

Journal:

Year:

2012

Language:

english

File:

PDF, 1.74 MB

english, 2012

25

Mitochondrial fragmentation and neuronal cell death in response to the Bcl-2/Bcl-xL/Bcl-w antagonist ABT-737

Kenneth W. Young, Lucia G.P. Piñón, Dalbir Dhiraj, Davina Twiddy, Marion MacFarlane, John Hickman, Pierluigi Nicotera

Journal:

Neuropharmacology

Year:

2010

Language:

english

File:

PDF, 1.89 MB

english, 2010

26

Caspases-3 and -7 are activated in goniothalamin-induced apoptosis in human Jurkat T-cells

Salmaan H. Inayat-Hussain, Annuar B. Osman, Laily B. Din, Abdul M. Ali, Roger T. Snowden, Marion MacFarlane, Kelvin Cain

Journal:

Year:

1999

Language:

english

File:

PDF, 202 KB

english, 1999

27

Serial comparison in the glasgow ECG analysis program

Peter W. Macfarlane, Marion Podolski

Journal:

Journal of Electrocardiology

Year:

1986

Language:

english

File:

PDF, 135 KB

english, 1986

28

A stressed cell? Heat shock protein 70 offers protection

Marion MacFarlane

Journal:

Trends in Pharmacological Sciences

Year:

2000

Language:

english

File:

PDF, 112 KB

english, 2000

29

Compensatory caspase activation: a cautionary tale

Marion MacFarlane

Journal:

Trends in Pharmacological Sciences

Year:

2001

Language:

english

File:

PDF, 16 KB

english, 2001

30

Promoter-specific or all wRAPped up in the genome?

Marion MacFarlane

Journal:

Trends in Pharmacological Sciences

Year:

2001

Language:

english

File:

PDF, 29 KB

english, 2001

31

OMInously, a mitochondrial serine protease is now unveiled as the third ‘MAC’

Marion MacFarlane

Journal:

Trends in Pharmacological Sciences

Year:

2001

Language:

english

File:

PDF, 24 KB

english, 2001

32

HIPPI–HIP1 – a deadly duo

Marion MacFarlane

Journal:

Trends in Pharmacological Sciences

Year:

2002

Language:

english

File:

PDF, 15 KB

english, 2002

33

SMAC agonists blaze the TRAIL to tumor cells

Marion MacFarlane

Journal:

Trends in Pharmacological Sciences

Year:

2002

Language:

english

File:

PDF, 31 KB

english, 2002

34

Caspase Activation Inhibits Proteasome Function during Apoptosis

Xiao-Ming Sun, Michael Butterworth, Marion MacFarlane, Wolfgang Dubiel, Aaron Ciechanover, Gerald M Cohen

Journal:

Year:

2004

Language:

english

File:

PDF, 609 KB

english, 2004

35

Glucose—a sweet way to die

MacFarlane, Marion, Robinson, Gemma L., Cain, Kelvin

Journal:

Year:

2012

Language:

english

File:

PDF, 939 KB

english, 2012

36

DNA degradation and proteolysis in thymocyte apoptosis

Howard O. Fearnhead, Marion MacFarlane, David Dinsdale, Gerald M. Cohen

Journal:

Toxicology Letters

Year:

1995

Language:

english

File:

PDF, 590 KB

english, 1995

37

TRAIL-induced signalling and apoptosis

Marion MacFarlane

Journal:

Toxicology Letters

Year:

2003

Language:

english

File:

PDF, 241 KB

english, 2003

38

Isolation, characterisation and reconstitution of cell death signalling complexes

Hughes, Michelle A., Langlais, Claudia, Cain, Kelvin, MacFarlane, Marion

Journal:

Year:

2013

Language:

english

File:

PDF, 768 KB

english, 2013

39

Pulmonary toxicity of carbon nanotubes and asbestos — Similarities and differences

Donaldson, Ken, Poland, Craig A., Murphy, Fiona A., MacFarlane, Marion, Chernova, Tatyana, Schinwald, Anja

Journal:

Advanced Drug Delivery Reviews

Year:

2013

Language:

english

File:

PDF, 979 KB

english, 2013

40

Encyclopedia of Life Sciences || Death Receptors at the Molecular Level: Therapeutic Implications

MacFarlane, Marion

Year:

2001

Language:

english

File:

PDF, 459 KB

english, 2001

41

Factors associated with self-efficacy for managing recovery in the trauma intensive care population: A prospective cohort study

Connolly, Fiona R., Aitken, Leanne M., Tower, Marion, Macfarlane, Bonnie

Journal:

Year:

2014

Language:

english

File:

PDF, 369 KB

english, 2014

42

Processing/Activation of at Least Four Interleukin-1β Converting Enzyme-like Proteases Occurs during the Execution Phase of Apoptosis in Human Monocytic Tumor Cells

Marion MacFarlane, Kelvin Cain, Xiao-Ming Sun, Emad S. Alnemri and Gerald M. Cohen

Journal:

The Journal of Cell Biology

Year:

1997

Language:

english

File:

PDF, 2.63 MB

english, 1997

43

The Inhibitor of Apoptosis Protein-Binding Domain of Smac Is Not Essential for Its Proapoptotic Activity

Darren L. Roberts, Wendy Merrison, Marion MacFarlane and Gerald M. Cohen

Journal:

The Journal of Cell Biology

Year:

2001

Language:

english

File:

PDF, 1.12 MB

english, 2001

44

Investigating the roles of lysosomal iron and reactive oxygen species in the onset of mitochondrial toxicity induced through endoperoxide antimalarial drugs

Firman, James, Cain, Kelvin, Park, B. Kevin, MacFarlane, Marion, Chadwick, Amy

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 78 KB

english, 2014

45

Targeting the rate limiting step of protein synthesis may provide an alternative approach to overcome the chemoresistance of malignant mesothelioma

Grosso, Stefano, George, Gifty M., Chernova, Tatyana, Sun, Xiao Ming, Murphy, Fiona A., Sbarrato, Thomas, Dudek, Kate, Bennett, Jonathan, Nakas, Apostolos, Bushell, Martin, MacFarlane, Marion, Willis,

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 64 KB

english, 2014

46

Role of pro-inflammatory cells in mesothelial cell oncogenesis induced by toxic fibres

Chernova, Tatyana, Murphy, Fiona, Kumar, Pavithra, Sun, Xiao Ming, Galavotti, Sara, Grosso, Stefano, Bennett, Jonathan, Nakas, Apostolos, Bushell, Martin, MacFarlane, Marion, Willis, Anne

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 66 KB

english, 2014

47

Predicting sensitivity to PI3K/mTOR inhibition in asbestos-induced malignant mesothelioma models

Powley, Ian, Galavotti, Sara, Sun, Xiao-Ming, Chernova, Tatyana, Nakas, Apostolos, Le Quesne, John, Pringle, Howard, Fennell, Dean, MacFarlane, Marion

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 77 KB

english, 2014

48

‘Aerobically poised’ leukaemia cells are resistant to the mitochondrial toxin and BCL-2/BCL-XL inhibitor, ABT-737

Miles, Gareth, Langlais, Claudia, MacFarlane, Marion, Cain, Kelvin

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 65 KB

english, 2014

49

SMAC mimetics in combination with the pro-inflammatory cytokine TNFα augment cell death in B-13 progenitor-derived hepatocytes

Hayward, Giles M., Wallace, Heather M., Wright, Matthew C., MacFarlane, Marion

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 66 KB

english, 2014

50

Modulation of the Sensitivity of Jurkat T-Cells to Inhibition of Protein Synthesis by Tumor Necrosis Factor α-Related Apoptosis-Inducing Ligand

Elia, Androulla, Powley, Ian R., MacFarlane, Marion, Clemens, Michael J.

Journal:

Journal of Interferon & Cytokine Research

Year:

2014

Language:

english

File:

PDF, 425 KB

english, 2014

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